An ex-NYPD officer-turned-sheriff of a small rural Georgia town has to contend with a gang of thieves who have taken a wealthy doctor hostage.

Caleb and his six college friends are getting ready for the Halloween Party of their lives when they accidentally unleash a secret biological serum into the small rural town of Lakeshear. The serum transforms its victims into rabid mindless killers. Caleb unknowingly infected himself and must reach out to his friends to find a cure for this deadly infection before it's too late. Who created the serum? And what lengths will these seven friends have to go to in order to stop the deadly spread?